When microglia cells are activated and overproliferate in the brain, there are disorders in the signal transmission system between nerve cells, disorders in the pruning of nerve cell synapses, the balance in the synaptic transmission and arousal system is disrupted, and it is in over-stimulation or suppression modes. Disruptions and deteriorations occur in many tasks and functions of microglia cells related to nerve cells and signal transmission systems. It has been reported that there are disorders in the signal transmission systems of nerve cells in the brain in autism. As a result of the increase in the number of microglia cells and cell type changes, it has been reported that there are transmission problems, delays, and disruptions in transmissions in the signal transmission systems related to nerve cells in the brain in autism.