Çalışma Prensipleri – Working Principles

1. Holistic Medical Approach and Applications

Microorganisms found in different ecosystems of the human body are called microbiota. Intestinal microbiota is important in ensuring the integrity of the intestinal epithelium and determining which molecules will pass into the blood. Microbiota imbalances (dysbiosis) and inflammation in the intestines allow harmful microorganisms, toxins, or undigested food particles to pass from the intestines into the blood, causing leaky intestines. Substances that reach the bloodstream trigger an inflammatory response in the body that can cause various diseases, affecting the nervous system and immune system. As a result, disorders of the content and functions of the intestinal microbiota either trigger or contribute to the development of illnesses and disorders in the brain, intestine, and numerous other systems of the human body.

First of all, it is possible to control inflammation in the brain and outside the brain by repairing the intestinal barrier with a microbiota-centered approach. The human intestinal microbiota and the preservation or gain of intestinal health; They have very important and critical roles in terms of protecting health and/or healing diseases and are part of healing mechanisms.

2. Multidisciplinary Approach

Intestinal microbiota affects the intestine, liver, brain, and other organs at the molecular level. It also acts as a barrier. It can affect metabolism by regulating absorption, digestion, intestinal motility, and mucosal immunity. The digestive system is strongly stimulated by neurons located in the intestine (enteric) and outside the intestine. For this reason, intestinal microbiota regulates many functions in the body and works together with the central nervous system.

The Microbiota-Gut-Brain Axis has been the subject of numerous studies in various nations in recent years. The existence of a two-way interaction and medical communication between the human intestinal microbiota and the brain has been determined. Intestinal microbiota affects neurons in the central nervous system via enteric neurons by producing various metabolites, regulating the physiology and metabolism of the host. This bilateral neural current also affects autonomic functions, brain function, motor coordination, emotion, temperature regulation, behavior, and cognition; it functions through the gut-brain axis.

The relationship between intestinal microbiota balance and many systemic diseases has been demonstrated by scientific studies. Systemic diseases related to intestinal health and microbiota balance are listed below:

• Irritable Bowel Syndrome-IBS
• Inflammatory Bowel Diseases-IBD (Ulcerative Colitis, Crohn’s Disease)
• Asthma, Allergy
• Neuro-Psychiatric Diseases (Anxiety, Depression)
• Neuro-Developmental Disorders (Autism, Schizophrenia)
• Neuro-Degenerative Diseases (Alzheimer’s Disease, Dementia, Parkinson’s, Multiple Sclerosis-MS)
• Endocrine Diseases (Type 1 and Type 2 Diabetes-DM, Hypertension)
• Addictions (Alcohol and Food Addiction)
It is possible to contribute to both the prevention and the treatment of these diseases with multidisciplinary work and intestinal microbiota adjustments.

3. Individualized (hyper-personalized) and Evidence-Based Treatment

Although the microorganisms that make up the microbiota (bacteria, fungi, and viruses) are similar to each other in terms of species; the content, amount and composition of the species are different in each person. Each person’s microbiome profile is unique like a fingerprint. By interpreting individualized microbiome profile analyses and using scientific information discovered about microbiome member bacteria, an accurate and successful treatment can be achieved by intervening in the microbiota. Intestinal microbiota disorders are the result of the disruption of the balance in the number and diversity of species in microbiota member bacteria. Under the guidance of scientific information, the microbiota balance can be restored by reestablishing the disturbed balance in light of individual microbiome profile data gathered from microbiome analyses.

4. Organic Certified Active Ingredients and Natural Plant-Based Treatment

Treatment is applied with organic certified active ingredients and natural plant products, which are free from the side effects that synthetic and chemical substances may create or some chemical toxic effects, and whose effectiveness has been proven by scientific research and published scientific articles; and whose doses, serum half-lives, bioavailability, and pharmacological properties have been investigated.

5. Laboratory Analyses and Comments

General screening tests are requested for the purpose of evaluating the health status. The necessity of special analyses is decided after the individualized (hyper-personalized) medical evaluation.