- Increased permeability of the gut-brain barrier
- Imbalances in the number and diversity of bacteria in the gut microbiota
- Dysfunction in bacterial groups within the gut microbiota that have significant functions (histaminergic bacteria, LPS-producing bacteria that induce and initiate inflammation, neuroactive microbiota, etc.)
- Mitochondrial dysfunctions in ATP synthesis; energy metabolism disorders
- DNA methylation disorders
- Triggering of epigenetic changes
- Allergic tendencies
- Especially food allergies, food intolerances
- Functional gastrointestinal problems; often constipation, rarely diarrhea, etc.
- Eating disorders and related weight control problems, insulin resistance, and glucose metabolism disorders
- Sleep disorders at night
- Diet and nutritional disorders
- Accumulation of toxic (heavy) metals in blood and cells
- Activation of inflammation
- Activation of oxidative and nitrosative stress
- Accumulation of free radicals and reactive oxygen species (ROS)
- Imbalances in trace elements and minerals (often zinc deficiency and selenium deficiency, etc.)
- Tendencies toward epilepsy
- Attention deficit or attention deficit hyperactivity disorders (ADHD)
- Other comorbid neuropsychiatric problems (anxiety, depression, obsessive-compulsive disorders (OCD), etc.)








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