The mother’s intestinal microbiota composition (balance) disorders, intestinal permeability, blood-brain barrier permeability, inflammation activation and uncontrolled activation of oxidative stress pathways during the pre-pregnancy or trimester periods of pregnancy are closely related to the child’s health/risk of developing certain diseases.

The healthy conclusion from this may be as follows: It may be recommended that expectant mothers be healthy and balanced in terms of intestinal microbiota balance, intestinal permeability, blood-brain barrier permeability, inflammation activation and oxidative stress pathway activation before pregnancy. It may contribute to reducing the risks of certain diseases that may be seen in the child in the future. In the perinatal period, the mother’s intestinal microbiota disorders (dysbiosis) are critical determinants in fetal neurodevelopmental and behavioral disorders and social communication skills disorders.