An analysis of the total DNA amount of microorganisms belonging to the gut microbiota was conducted, and it was determined that 93% of them were bacteria, 5.8% were viruses, 0.1% were fungi, and the remaining 1.1% belonged to others (archaea and protists).

Important conclusions can be drawn from this;

1. When we talk about the gut microbiome, bacteria come to mind, and this is correct (93% of the total DNA).

2. The fungi present in the gut microbiota constitute a very small part. (0.1% of the total DNA)

Based on these facts, the following conclusions can be drawn;

1. The first thing that comes to mind in the imbalance of gut microbiota is the imbalance of bacteria; however, successful results can be obtained from these adjustments with probiotics containing bacterial types that are suitable for accurate matching with the individual’s microbiome profile.

2. It is quite difficult to successfully regulate the imbalances related to the entire bacteria present in the microbiota directly with probiotics that only contain yeast species (e.g., Saccharomyces boulardii, Saccharomyces cerevisiae).

Because; all fungi constitute only 0.1% (one-tenth) of the microbiota.

3. It is quite difficult to successfully regulate imbalances related to the balance of yeast fungi, especially Candida albicans, with probiotics that only contain bacterial strains.